How Can Polynucleotides Improve My Skin?

If you’ve been hearing the word Polynucleotides everywhere lately and wondering what they actually are and why everyone in London seems to be having them, you’re not alone.

Polynucleotide treatments are a next-level skin treatment that work from the inside out. Unlike fillers, which just add volume, or skin boosters, which focus mainly on hydration, Polynucleotides actually help your skin repair and regenerate itself at a cellular level.

At Emporium Treatment Clinic in the heart of Marylebone, Polynucleotide treatments have quickly become a go-to for clients who want true skin regeneration, not just a quick glow.

What Are Polynucleotides?

Polynucleotides are purified chains of nucleotides, the building blocks of DNA which are specially prepared for aesthetic use. Once they are injected into the skin, they kickstart your body’s natural repair process and support long-term rejuvenation.

The treatment is delivered through precise, tiny injections into the skin. It’s ideal for concerns like ageing, loss of elasticity, scarring, and even delicate areas like the under-eye concerns. Once in the skin, Polynucleotides stimulate fibroblasts, the cells responsible for producing collagen and elastin. That means firmer, stronger, more lifted skin over time, plus improved texture and scar restructuring.

They also attract and bind water, which hydrates the skin while creating an antioxidant-rich environment that supports healing and tissue repair.

Most polynucleotide products used in aesthetics are derived from highly purified salmon DNA, chosen because it’s extremely biocompatible, making it both safe and effective.

The result? Healthier, fresher, revitalised skin, achieved through true regeneration rather than simply filling or volumising. The changes are subtle but powerful.

Polynucleotides are commonly used on the face, neck, eye areas, décolletage and hands.

Why Have Polynucleotides?

Their purpose is simple, to repair and regenerate the skin from within to:

• Stimulate fibroblasts (the cells responsible for collagen production)
• Improve skin elasticity
• Strengthen thinning or fragile skin
• Reduce fine lines
• Improve skin texture and tone
• Support tissue repair
• Reduce scar tissue

In short, they encourage your skin to behave like younger, healthier skin.

At Emporium Treatment Clinic, clients often choose Polynucleotides when they want more than surface-level improvement. This treatment is especially popular for:

• Under-eye rejuvenation
• Crepey or thinning skin
• Early signs of ageing
• Acne scarring
• Dull or tired-looking skin
• Preventative ageing
• Reduce fine lines & wrinkles
• Scar tissue

One of the standout areas for Polynucleotides is the delicate eye areas. Because they strengthen and repair rather than add volume, they are ideal for improving skin quality without puffiness and dark circles.

What Happens During A Polynucleotide Treatment?

Your appointment begins with a detailed consultation at Emporium Treatment Clinic.  Angela, an advanced Aesthetician will assess your skin, discuss your concerns, and create a tailored plan.
The treatment involves a series of small, precise injections into the targeted area. It usually takes around 30 minutes. Numbing cream can be used to ensure comfort.

After treatment, you may experience:

• Mild swelling
• Small raised bumps (these usually settle within 24–48 hours)
• Occasional light bruising

Downtime is minimal, but you may prefer to avoid major social plans for a few days.

How Many Polynucleotide Treatments Are Needed?

Depending on your age and skin concern Polynucleotides are typically done as a course of 2 to 3 treatments, spaced about 3 to 4 weeks apart. This is because they work by stimulating the body’s natural regenerative processes and that takes time.

Most clients start noticing improvements in skin texture and firmness within a few weeks, with continued improvement over several months as collagen production increases.

Results can last 6 to 12 months, depending on your skin, age, diet and lifestyle. Many clients return for maintenance once or twice a year to keep their skin strong and resilient.

A younger or healthier skin would benefit from a single regenerative Polynucleotide boost.

Who Are Polynucleotide Treatments Actually For?

Honestly? Pretty much everyone.

Because they are so versatile and can be delivered using different injection techniques, Polynucleotide treatments are suitable for all skin types and a wide range of skin concerns.

If your goal is healthier-looking skin, more radiance, better texture, or that subtle youthful bounce, Polynucleotides are a great option as they work by restoring overall skin quality. And because of their versatility they can be used for targeting one single issue.

They are especially beneficial for anyone dealing with acne scars or other types of scarring. By stimulating collagen and supporting tissue repair, they help improve skin texture and gradually soften the appearance of scars over time.

Polynucleotides are ideal if you:

• Want natural-looking rejuvenation
• Prefer regeneration over added volume
• Are concerned about delicate or thinning skin
• Want a long-term skin health approach

At Emporium Treatment Clinic in Marylebone, the focus is always on subtle, refined results. Polynucleotides don’t change your features, they improve your skin quality so you look fresher, younger and feel more confident.

Do Polynucleotide Injections Really work?

Yes, Polynucleotide treatments have an excellent success rate. Here at Emporium Treatment Clinic our clients that have received Polynucleotide treatments are very pleased with the results.

It is important that the treatment procedure is fully explained prior to treatments and the client expectations can be achieved.

Where Can I Get Polynucleotides Injections In Marylebone, London?

If you’re experiencing any skin concerns or would like to learn more about your options, we encourage you to seek professional guidance.

At Emporium Treatment Clinic, our advanced aesthetician, Angela, brings over 37 years of experience and is here to provide expert advice and personalised care to support your skin journey.

Contact Angela For Advice: 07930661971

Author: Angela Taffinder the founder of Emporium Treatment Clinic. A practising Aesthetician for 35+ years, holistic and wellbeing advocate and yoga instructor. The creator of Yoga & Vitality.